Lamellar ichthyosis is a are inherited skin disorer. When the affected baby is born, the skin is covered by a shiny, waxy-appearing outer membrane. The membrane sheds in 10–14 days after birth. The patient's skin has extensive scaling caused by hyperkeratosis. When patients get older, the scaling tends to be concentrated around joints in areas such as the groin, the armpits, the inside of the elbow and the neck. The scales often tile the skin and may look like fish scales. There is no cure for lamellar ichthyosis, but the symptoms can be relieved by moisturizers, prevention of overheating, and eye drops (preventing eye drying). Severe case may need systemic retinoids (isotretinoin and acitretin).
How is Lamellar ichthyosis treated in practice?