Myelodysplastic syndrome is a blood-making disorder caused by abnormal hematopoietic stem cell proliferation and differentiation. Symptoms include reduced number of all blood cells in the peripheral blood, bone marrow cells over-growth, and abnormal mature and immature cells. 30% to 60% patients can develop into leukemia. Treatment usually focuses on reducing or preventing complications. In some cases, bone marrow transplant can help to extend life.
How is Myelodysplastic syndromes treated in practice?