Myelofibrosis is a type of chronic leukemia which affects blood cell production. Collagen tissue overgrows, seriously affecting hematopoietic function. Onset is usually subtle and the disease progresses slowly. Many patients are diagnosed in a few months or even years after symptoms appear. The most common symptoms are fagitue, weight loss and oppression by enlarged spleen. At first, the overall condition is still good. Gradually patients have symptoms of spleen enlargement, hyper-metabolism, and anemia. Later they may have bleeding symptoms. Treatment focuses on improving symptoms. Many options are available.
How is Myelofibrosis treated in practice?