Primary immunodeficiency is a group of congenital immune dysfunction diseases. It often occurs in infants and young children. It is often related to genetic factors. Main symptoms include recurrent infections, which may be life-threatening. Treatment focuses on prevention of infection and improves immunity. Patients should avoid contact with bacteria. If infected, antibiotics should be used proactively. Patients should not be given live attenuated vaccines because of risk of infection. For patients with cellular immune deficiency and combined immunodeficiency, thymosin can be used. Transplantation of thymus, bone marrow or stem cells can correct immunodeficiency.
How is Primary immunodeficiency treated in practice?